Etizolam (Atizolm) 1mg


Etizolam is a thienodiazepine, chemically related to benzodiazepines but with a benzene ring replaced by a thiophene ring. It acts as a full agonist at GABA-A receptors, exhibiting properties such as amnesia, anxiolysis, anticonvulsant effects, hypnotic properties, sedation, and muscle relaxation.

  • Etizolam (Atizolm) 1mg

    Etizolam (Atizolm) 1mg


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      Etizolam (Atizolm) 1mg

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      Etizolam is a thienodiazepine, chemically related to benzodiazepines but with a benzene ring replaced by a thiophene ring. It acts as a full agonist at GABA-A receptors, exhibiting properties such as amnesia, anxiolysis, anticonvulsant effects, hypnotic properties, sedation, and muscle relaxation.

      History and Availability

      Etizolam was first introduced in 1983 in Japan to treat neurological conditions like anxiety and sleep disorders. It’s marketed in Japan, Italy, and India but is not FDA-approved in the US. However, it remains unscheduled in several states and is legally available for research purposes.

      Mechanism of Action

      Etizolam enhances GABAergic transmission by selectively binding to GABA-A receptors, leading to increased chloride currents. It binds to the benzodiazepine binding site located across the interface between alpha and gamma subunits, with high affinity for receptors containing alpha 1 beta 2 gamma 2S subunit combinations.

      Medical Uses

      Estazolam, a benzodiazepine, is primarily used for short-term treatment of insomnia, typically for 7 to 10 days. It belongs to the group of central nervous system depressants and is available only with a doctor’s prescription.

      Precautions and Considerations

      Before using Estazolam, it’s essential to consider allergies, pediatric and geriatric use, and potential drug interactions. Special caution is advised for individuals with a history of alcohol or drug abuse, breathing problems, lung disease, depression, kidney disease, or liver disease.

      Dosage and Administration

      The dosage of Estazolam varies based on factors like age and medical condition. It’s usually taken just before bedtime. Missed doses should be taken as soon as remembered, but doubling up on doses should be avoided. Proper storage is also important to maintain medication efficacy.

      Side Effects and Overdose

      The side effects of Etizolam (Atizolm) 1mg can vary in frequency and severity. More common side effects include decreased body movement, clumsiness, dizziness, and sleepiness, while less common ones encompass dry mouth, headache, and mood changes. Rare side effects may include aggressive behavior, chest pain, and seizures. Some side effects may require immediate medical attention, such as changes in consciousness or irregular breathing. Other less severe side effects, like muscle pain or changes in vision, may not necessitate medical intervention but should still be monitored. Additionally, certain side effects, like increased sensitivity to sunlight or skin redness, may occur with an unknown frequency.

      Interactions with Other Substances

      Estazolam may interact with various medications, including CNS depressants, alcohol, and tobacco, leading to increased sedation and other adverse effects. It’s important to discuss all current medications, including prescription, over-the-counter, and herbal supplements, with a healthcare provider to avoid potential interactions.

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      Is estazolam a sleeping pill?

      Estazolam is indeed utilized as a short-term treatment for insomnia, aiding individuals who struggle with falling asleep or staying asleep. As a member of the benzodiazepine class of medications, estazolam operates by slowing down brain activity to facilitate sleep.

      What time should I take estazolam?

      For optimal effectiveness, estazolam should be taken just before bedtime, precisely when you are prepared to sleep. It’s important to carefully read and adhere to the instructions provided in the Medication Guide accompanying the medicine, and if any queries arise, consulting your doctor is advisable.

      Is it safe to take estazolam?

      While estazolam can effectively address sleep issues, it’s crucial to be aware of potential side effects, including the risk of developing suicidal thoughts or behaviors, particularly for individuals with a history of depression. If you or those around you observe any unusual changes in behavior or thoughts, seeking medical assistance promptly is recommended.

      Can I take etizolam daily?

      The usage of etizolam daily can lead to both mental and physical dependence on the drug. Reports suggest that noticeable effects may result in dependency within a timeframe ranging from two weeks to a month of regular use. Therefore, cautious and monitored administration of etizolam is advisable to mitigate the risk of addiction and associated complications.

      Generic Name : Atizolm Brand Name : Etizolam Strength : 1 mg Manufactured by  Signature Drug Class : Antihistamines

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